منابع مشابه
How Cells Cope with Obesity
Currently, more than 2.7 million American adults are diagnosed as obese each year. Many of these people suffer from a disorder known as metabolic syndrome, which includes symptoms like hypertension and elevated blood cholesterol. They are also at risk for developing additional diseases such as heart disease and diabetes mellitus. In fact, obesity may be a major cause of all these problems ... t...
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Introduction “The UK has the second highest prevalence of obesity in the world, and something needs to be done about it.” These words were uttered by Sir Richard Thompson (President of the Royal College of Physicians [RCP]) in an introduction to a recent RCP working party report, Action on obesity: comprehensive care for all [1]. A key recommendation of the working party is that the healthcare ...
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The ability of cells to fully and faithfully replicate DNA is essential for preventing genomic instability and cancer. DNA is susceptible to damage both in resting and in actively replicating cells. Thus, genome duplication necessarily involves replication of damaged DNA. The many mechanism cells use to avoid or overcome the problems of replicating an imperfect DNA template are discussed.
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Since the dawn of life on Earth some four billions of years ago, gravity has been a more or less stable environmental factor thus influencing the phylogenetic development of all living organisms. On the one side, gravity represents a factor of physical restriction, which compelled the ancestors of all extant living beings to develop basic achievements to counter the gravitational force (e.g., e...
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"Some technologies are indeed making the world a riskier place . . . as innovations that can scupper the best laid business plans." The Economist, Jan 24, 2004 "Living Dangerously" p. 3 The gap between the exponential growth of technology, and the slow process of it's understanding and proper adaption to human and business benefit, is analyzed. Present day developments are compared with the rec...
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ژورنال
عنوان ژورنال: PLoS Biology
سال: 2011
ISSN: 1545-7885
DOI: 10.1371/journal.pbio.1001077